How to clear the cache for Outlook (2025)
Updated: 12/10/2025
Article #: 210
Open File Explorer
C: Users
Click on the User profile you want to edit
AppData/Local/Microsoft/Outlook
Delete all .ost
Delete all .nst
Reboot
Launch Outlook again.
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Here is Joe's Krout suggestion
[6/15 9:17 AM] Joe Krout
OST File Corruption?
I have had several cases of Outlook locking up for users and either refusing to load their profile, or not accepting new messages from the server. I have been able to clear the issue by renaming/deleting the .ost file and .nst files from %USERPROFILE%\AppData\Local\Microsoft\Outlook. Outlook then loads a new copy the next time it is launched. Is anyone else encountering a similar issue?
Edited
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